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4.1 ) andthe central motor output that dictates a compen-satory increase in muscle tone. (b) Areasof correlated FDG-PETbinding representing glucosehypometabolism associatedwith MMSE scores. Theseenzymes selectively cleave DNA, generating small oligo-nucleosomal fragments.

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Open—communication between the lung and pleural space persists (bronchopleural fistula).Intrapleural pressure and atmospheric pressure are equal throughout the respiratory cycle, whichprevents re-expansionofthecollapsedlung.Hydropneumothoraxdevelops.Infectionis commonandempyema develops. Vlatkovic N, Guerrera S, Li Y, Linn S, Haines DS, Boyd MT (2000) MDM2 interacts with theC-terminus of the catalytic subunit of DNA polymerase epsilon.