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Therationale is: the incidence of resistant bacillito most drugs ranges from 10–8 to 10–6.Because an average patient of pulmonarytuberculosis harbours 108 to 1010 bacilli, thenumber of organisms that will not respond toa single drug is high and cannot be dealt bythe host defence.

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The mucous and serous cells are aligned to surround the acinus lumen.

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Patients with familialALS associated with an SOD1 mutation frequently havedegeneration of the posterior columns, Clarke’s column,and spinocerebellar tracts (Ince et al., 2008). This controversy has been attributed to theexistence of multiple splicing isoforms with distinct functions; the full-length TAisoform of p63 has structural and functional similarity to p53 (Fig.